Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TK1 | P04183 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424933 | 0.87 | POLB (0.61) | POLBTK1BCHE | |
| SCHEMBL4194754 | 0.85 | POLB (0.55) | POLBTK1BCHE | |
| SCHEMBL4731692 | 0.85 | RNASE1 (0.67) | POLBTK1BCHE | |
| SCHEMBL4731694 | 0.85 | RNASE1 (0.67) | POLBTK1BCHE | |
| SCHEMBL21886792 | 0.85 | RNASE1 (0.67) | POLBTK1BCHE | |
| SCHEMBL21886800 | 0.85 | RNASE1 (0.67) | POLBTK1BCHE | |
| SCHEMBL3694340 | 0.84 | POLB (0.64) | POLBTK1BCHE | |
| SCHEMBL14660646 | 0.83 | POLB (0.57) | POLBTK1BCHE | |
| SCHEMBL15216188 | 0.82 | POLB (0.64) | POLBTK1 | |
| SCHEMBL263767 | 0.82 | POLB (0.64) | POLBTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753002-A1 | MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS | AMGEN INC. (US) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026972-A1 | MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS | AMGEN INC. (US) | 1995-10-12 | — | — | WO | disclosed |