Glutarate

Glutarate

SCHEMBL8744382

C1CCCC1.O=C(O)CCCC(=O)O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 2/20 0.79
LMNA P02545 4/20 0.67
TSHR P16473 4/20 0.62
NFKB1 P19838 2/20 0.62
PMP22 Q01453 1/20 0.62
CYP1A2 P05177 2/20 0.56
MAPK1 P28482 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
CAMK2A Q9UQM7 1/20 0.56
ALKBH5 Q6P6C2 1/20 0.53
SUCNR1 Q9BXA5 1/20 0.53
EGLN1 Q9GZT9 1/20 0.53
GABRR3 A8MPY1 1/20 0.53
GABRP O00591 1/20 0.53
GABRD O14764 1/20 0.53
HDAC3 O15379 1/20 0.53
GABBR2 O75899 1/20 0.53
THRB P10828 1/20 0.53
GABRA1 P14867 1/20 0.53
GABRB1 P18505 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutarate SCHEMBL3859608 1.00 SLC22A6 (0.79) SLC22A6LMNATSHRNFKB1PMP22
Glutarate SCHEMBL27580861 1.00 SLC22A6 (0.79) SLC22A6LMNATSHRNFKB1PMP22
Glutarate SCHEMBL28290689 0.94 SLC22A6 (0.69) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL4353087 0.93 LMNA (0.79) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL5311340 0.93 LMNA (0.79) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL10764903 0.93 LMNA (0.79) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL8997800 0.90 LMNA (0.73) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL258769 0.90 LMNA (0.73) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL2791026 0.90 LMNA (0.73) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL2538446 0.90 LMNA (0.73) SLC22A6LMNATSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0752975-A1 ZEOLITES AND PROCESSES EMPLOYING THEM EXXON CHEMICAL PATENTS INC. (US) 1997-01-15 EP disclosed
EP-0710216-A1 PROCESS FOR THE MANUFACTURE OF A ZEOLITE EXXON CHEMICAL PATENTS INC. (US) 1996-05-08 EP disclosed
WO-1995026928-A1 ZEOLITES AND PROCESSES EMPLOYING THEM EXXON CHEMICAL PATENTS INC. (US) 1995-10-12 WO disclosed
WO-1995003249-A1 PROCESS FOR THE MANUFACTURE OF A ZEOLITE EXXON CHEMICAL PATENTS INC. (US) 1995-02-02 WO disclosed