SCHEMBL8744600

SCHEMBL8744600

[CH2]c1c(C#N)c(C#N)c(C#N)c(C#N)c1C#N

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57168 0.78 ALDH1A1 (0.47) MEN1ALDH1A1TP53CYP3A4MAPT
SCHEMBL5252143 0.71 ALDH1A1 (0.46) MEN1ALDH1A1TP53MAPTMAPK1
SCHEMBL10464742 0.67 TRPV4 (0.33)
SCHEMBL25311012 0.67 MEN1 (0.39) MEN1ALDH1A1TP53CYP3A4MAPT
SCHEMBL6512716 0.61 TRPV4 (0.39) MEN1ALDH1A1TP53CYP3A4MAPT
SCHEMBL21018280 0.61 MEN1 (0.35) MEN1ALDH1A1TP53CYP3A4MAPT
SCHEMBL16747678 0.61 ALDH1A1 (0.42) MEN1ALDH1A1TP53CYP3A4MAPT
SCHEMBL24070657 0.61 BPTF (0.36) MEN1ALDH1A1TP53CYP3A4MAPT
SCHEMBL21896579 0.61 MAPK1 (0.38) MEN1ALDH1A1TP53CYP3A4MAPT
SCHEMBL23522361 0.61 MEN1 (0.35) MEN1ALDH1A1TP53CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0753415-A2 Image forming method KONICA CORPORATION (JP) 1997-01-15 EP disclosed