SCHEMBL25311012

SCHEMBL25311012

N#Cc1c(C#N)c(C#N)c2c(C#N)c(C#N)c(C#N)c(C#N)c2c1C#N

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TRPV4 Q9HBA0 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30
CACNA1B Q00975 1/20 0.30
APBA1 Q02410 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57168 0.85 ALDH1A1 (0.47) MEN1ALDH1A1MAPTKMT2ATP53
SCHEMBL15061128 0.75 ALDH1A1 (0.38) MEN1ALDH1A1MAPTKMT2ATP53
SCHEMBL25312405 0.69
SCHEMBL25310855 0.69
SCHEMBL23522361 0.67 MEN1 (0.35) MEN1ALDH1A1MAPTKMT2ATP53
SCHEMBL21018280 0.67 MEN1 (0.35) MEN1ALDH1A1MAPTKMT2ATP53
SCHEMBL21896579 0.67 MAPK1 (0.38) MEN1ALDH1A1MAPTKMT2ATP53
SCHEMBL24070657 0.67 BPTF (0.36) MEN1ALDH1A1MAPTKMT2ATP53
SCHEMBL6512716 0.67 TRPV4 (0.39) MEN1ALDH1A1MAPTKMT2ATP53
SCHEMBL16747678 0.67 ALDH1A1 (0.42) MEN1ALDH1A1MAPTKMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230229077-A1 PHOTOACID GENERATOR FOR CHEMICALLY AMPLIFIED PHOTORESISTS FOR DEEP ULTRAVIOLET AND EXTREME ULTRAVIOLET LITHOGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION 2023-07-20 US claimed
US-20230229077-A1 PHOTOACID GENERATOR FOR CHEMICALLY AMPLIFIED PHOTORESISTS FOR DEEP ULTRAVIOLET AND EXTREME ULTRAVIOLET LITHOGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230229077-A1 PHOTOACID GENERATOR FOR CHEMICALLY AMPLIFIED PHOTORESISTS FOR DEEP ULTRAVIOLET AND EXTREME ULTRAVIOLET LITHOGRAPHY PAG1, GABRP, PGLS MEN1 4744/4885ALDH1A1 1489/4885MAPT 1994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.