Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.48 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27727745 | 0.85 | XDH (0.51) | CDC7DBF4CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL2822552 | 0.84 | CDC7 (0.68) | CDC7DBF4CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL877605 | 0.80 | XDH (0.51) | CDC7DBF4CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL27935663 | 0.77 | XDH (0.56) | CSNK2A2CSNK2BCSNK2A1RAB9AGAA | |
| SCHEMBL3101178 | 0.73 | HDAC1 (0.66) | CSNK2A2CSNK2BCSNK2A1RAB9AGAA | |
| SCHEMBL26759059 | 0.72 | XDH (0.56) | CSNK2A2CSNK2BCSNK2A1RAB9AGAA | |
| SCHEMBL16799006 | 0.71 | XDH (0.52) | CSNK2A2CSNK2BCSNK2A1RAB9AGAA | |
| Hydrochloric Acid SCHEMBL28424163 | 0.71 | XDH (0.55) | CSNK2A2CSNK2BCSNK2A1RAB9AGAA | |
| SCHEMBL21229137 | 0.68 | XDH (0.49) | CSNK2A2CSNK2BCSNK2A1RAB9AGAA | |
| SCHEMBL23794795 | 0.68 | CDC7 (0.79) | CDC7DBF4RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |