Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27727745 | 0.79 | XDH (0.51) | XDHCSNK2A2CSNK2BCSNK2A1RAB9A | |
| SCHEMBL27935663 | 0.72 | XDH (0.56) | XDHCSNK2A2CSNK2BCSNK2A1RAB9A | |
| Hydrochloric Acid SCHEMBL28424163 | 0.71 | XDH (0.55) | XDHCSNK2A2CSNK2BCSNK2A1RAB9A | |
| SCHEMBL877605 | 0.71 | XDH (0.51) | XDHCSNK2A2CSNK2BCSNK2A1RAB9A | |
| SCHEMBL2822552 | 0.71 | CDC7 (0.68) | XDHCSNK2A2CSNK2BCSNK2A1RAB9A | |
| SCHEMBL84030 | 0.71 | GAA (0.62) | RAB9AMAPTGAAALDH1A1LMNA | |
| SCHEMBL874462 | 0.71 | CDC7 (0.48) | XDHCSNK2A2CSNK2BCSNK2A1RAB9A | |
| SCHEMBL20641472 | 0.70 | XDH (0.68) | XDHCSNK2A2CSNK2BCSNK2A1RAB9A | |
| SCHEMBL20379759 | 0.70 | XDH (0.76) | XDHRAB9AMAPTGAAKDM4E | |
| SCHEMBL26759059 | 0.70 | XDH (0.56) | XDHCSNK2A2CSNK2BCSNK2A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3077373-B1 | PREPARATION OF COBICISTAT INTERMEDIATES | MYLAN LABORATORIES LTD (IN) | 2018-09-12 | — | — | EP | disclosed |
| US-9975864-B2 | Preparation of cobicistat intermediates | MYLAN LABORATORIES LIMITED (IN) | 2018-05-22 | — | — | US | disclosed |
| US-20160297780-A1 | Preparation of Cobicistat Intermediates | Mylan Laboratories Ltd. (IN) | 2016-10-13 | — | — | US | disclosed |
| EP-3077373-A1 | PREPARATION OF COBICISTAT INTERMEDIATES | Mylan Laboratories Ltd. (IN) | 2016-10-12 | — | — | EP | disclosed |
| WO-2015083066-A1 | PREPARATION OF COBICISTAT INTERMEDIATES | Mylan Laboratories Ltd. (IN) | 2015-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160297780-A1 | Preparation of Cobicistat Intermediates | PARP8, PARP9, PRSS8 | XDH 1143/4885CSNK2A2 361/4885CSNK2B 548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.