Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27727745 | 0.86 | XDH (0.51) | XDHGAAMGAMSIMGAM2 | |
| SCHEMBL2822552 | 0.83 | CDC7 (0.68) | XDHGAACDC7DBF4RAB9A | |
| SCHEMBL27935663 | 0.83 | XDH (0.56) | XDHGAAMGAMSIMGAM2 | |
| SCHEMBL874462 | 0.80 | CDC7 (0.48) | XDHGAACDC7DBF4RAB9A | |
| SCHEMBL3101178 | 0.78 | HDAC1 (0.66) | XDHGAAMGAMSIMGAM2 | |
| SCHEMBL18641386 | 0.73 | MAPT (0.48) | XDHGAAMGAMSIMGAM2 | |
| SCHEMBL3075528 | 0.73 | XDH (0.57) | XDHGAAMGAMSIMGAM2 | |
| SCHEMBL20641472 | 0.72 | XDH (0.68) | XDHGAAMGAMSIMGAM2 | |
| SCHEMBL16799006 | 0.71 | XDH (0.52) | XDHGAAMGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL18641355 | 0.70 | XDH (0.55) | XDHGAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |