⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16892250 | 0.81 | — | — | |
| SCHEMBL954216 | 0.81 | — | — | |
| SCHEMBL2517712 | 0.79 | FFAR1 (0.49) | — | |
| SCHEMBL28109155 | 0.78 | PARP15 (0.43) | — | |
| SCHEMBL16887640 | 0.78 | RAB9A (0.40) | — | |
| SCHEMBL13851671 | 0.76 | FFAR1 (0.43) | — | |
| SCHEMBL16886384 | 0.76 | RAB9A (0.39) | — | |
| SCHEMBL4095559 | 0.74 | SMN1; SMN2 (0.54) | — | |
| SCHEMBL19475116 | 0.72 | RAB9A (0.40) | — | |
| SCHEMBL9367356 | 0.71 | SLC6A3 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107857740-A | The synthetic method of the thiazolyl acetic acid of 2 sulfydryl of Cefodizime Sodium intermediate, 4 methyl 5 | 山东金城医药化工有限公司 | 2018-03-30 | — | — | CN | claimed |
| CN-102648199-A | Piperidine compound and use thereof | ASTRAZENECA AB | 2012-08-22 | — | — | CN | claimed |
| JP-2007522178-A | — | — | 2007-08-09 | — | — | JP | claimed |
| EP-1740568-A2 | BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES USEFUL FOR THE TREATMENT OF CARDIOVASCULAR DISEASE. | SMITHKLINE BEECHAM CORPORATION (US) | 2007-01-10 | — | — | EP | claimed |
| WO-2005077926-A2 | BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES USEFUL FOR THE TREATMENT OF CARDIOVASCULAR DISEASE | SMITHKLINE BEECHAM CORPORATION (US) | 2005-08-25 | — | — | WO | claimed |
| US-12559462-B2 | Pyrimidine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-20250368614-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | Opna Bio SA (CH) | 2025-12-04 | — | — | US | disclosed |
| EP-4654969-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | Opna Bio SA (CH) | 2025-12-03 | — | — | EP | disclosed |
| US-20250270172-A1 | Pyrimidine Derivatives As Modulators of the 5-HT2A Serotonin Receptor Useful For The Treatment of Disorders Related Thereto | ARENA PHARMACEUTICALS, INC. (US) | 2025-08-28 | — | — | US | disclosed |
| EP-4236937-B1 | PYRIMIDINE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024159067-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | Opna Bio SA (CH) | 2024-08-02 | — | — | WO | disclosed |
| US-20230157952-A1 | METHOD FOR IMPROVING THE STABILITY OF A PHARMACEUTICAL COMPOSITION COMPRISING A HIGH PENETRATION DRUG, AND THE PHARMACEUTICAL COMPOSITION OBTAINED THEREFROM | TECHFIELDS INC. (US) | 2023-05-25 | — | — | US | disclosed |
| EP-0159899-A2 | Cephalosporin esters, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-10-30 | — | — | EP | disclosed |
| EP-0137403-A2 | Carbapenems, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-04-17 | — | — | EP | disclosed |
| EP-0037710-B1 | THIAZOLE DERIVATIVES | JOHN WYETH & BROTHER LIMITED (GB) | 1984-08-01 | — | — | EP | disclosed |
| US-4385059-A | 4-(4-CHLOROPHENYL)-2-(4-HYDROXYPHENYL)THIAZOLE-5-ACETIC ACID | JOHN WYETH AND BROTHER LIMITED (GB) | 1983-05-24 | — | — | US | disclosed |
| US-4356185-A | ANTIINFLAMMATORY AGENTS | JOHN WYETH & BROTHER LIMITED (GB) | 1982-10-26 | — | — | US | disclosed |
| EP-0037710-A1 | Thiazole derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1981-10-14 | — | — | EP | disclosed |
| US-4203896-A | WITH MERCURIC ACETATE AND ACETIC ACID, ACIDIC HYDROLYSIS OF N-PROPENYL GROUP | ELI LILLY AND COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4144232-A | Substituted azetidin-2-one antibiotics | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |