Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11506303 | 0.73 | POLB (0.60) | RAB9ANPC1PTPN1ALDH1A1NPSR1 | |
| SCHEMBL8296400 | 0.71 | RAB9A (0.49) | RAB9ANPC1PTPN1HTR7PLOD2 | |
| SCHEMBL765420 | 0.70 | SLC6A3 (0.51) | SLC6A3SLC6A2RAB9ANPC1LTA4H | |
| SCHEMBL4778027 | 0.70 | RAB9A (0.43) | RAB9ANPC1PTPN1HTR7PLOD2 | |
| SCHEMBL9135960 | 0.70 | RAB9A (0.44) | RAB9ANPC1PTPN1HTR7PLOD2 | |
| SCHEMBL954216 | 0.70 | — | — | |
| SCHEMBL16892250 | 0.70 | — | — | |
| SCHEMBL2645324 | 0.69 | LTA4H (0.58) | RAB9ANPC1PTPN1HTR7PLOD2 | |
| SCHEMBL9663067 | 0.69 | RAB9A (0.54) | RAB9ANPC1PTPN1HTR7PLOD2 | |
| SCHEMBL6201900 | 0.69 | RAB9A (0.59) | RAB9ANPC1PTPN1HTR7PLOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395174-B1 | Thiazole derivatives | SHELL INT RESEARCH (NL) | 1994-12-07 | — | — | EP | disclosed |
| US-5089512-A | Fungicides | SHELL RESEARCH LIMITED (GB) | 1992-02-18 | — | — | US | disclosed |
| EP-0395174-A2 | Thiazole derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-10-31 | — | — | EP | disclosed |