SCHEMBL8744688

SCHEMBL8744688

COCCc1c[nH]c(C#N)n1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8744758 0.77
SCHEMBL5069930 0.76
SCHEMBL8744749 0.72 GRM5 (0.31)
SCHEMBL1971726 0.65
SCHEMBL4265783 0.65 CHRNB2 (0.33) HCAR2
SCHEMBL24117442 0.63 HCAR2 (0.32) HCAR2
SCHEMBL157 0.63 CACNA1H (0.33) HCAR2
SCHEMBL6183903 0.62 HCAR2 (0.32) HCAR2
SCHEMBL24762730 0.62
SCHEMBL3443720 0.62 BACE1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0653421-B1 Process for preparing 2-cyanoimidazole compounds ISHIHARA SANGYO KAISHA (JP) 1997-01-15 EP disclosed
US-5552557-A Process for preparing 2-cyanoimidazole compounds by reaction of an amino ketone compound ISHIHARA SANGYO KAISHA, LTD. (JP) 1996-09-03 US disclosed
EP-0653421-A1 Process for preparing 2-cyanoimidazole compounds ISHIHARA SANGYO KAISHA LTD. (JP) 1995-05-17 EP disclosed