SCHEMBL4265783

SCHEMBL4265783

COCCc1cncc(CCOC)n1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
HCAR2 Q8TDS4 1/20 0.31
PDE2A O00408 1/20 0.30
PDE8A O60658 1/20 0.30
PDE5A O76074 1/20 0.30
PDE9A O76083 1/20 0.30
PDE6A P16499 1/20 0.30
HTR2C P28335 1/20 0.30
HTR7 P34969 1/20 0.30
HTR2B P41595 1/20 0.30
PDE1B Q01064 1/20 0.30
PDE4D Q08499 1/20 0.30
PDE7A Q13946 1/20 0.30
PDE3A Q14432 1/20 0.30
PDE11A Q9HCR9 1/20 0.30
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32666839 0.86 CDK2 (0.38) CHRNB2CHRNA4
SCHEMBL4265784 0.86 CYP11B2 (0.34) CHRNB2CHRNA4
SCHEMBL16755476 0.86 NOS1 (0.38)
SCHEMBL4264181 0.77 LMNA (0.38)
SCHEMBL4266146 0.76 KDM4E (0.42)
SCHEMBL9797653 0.72 NOS3 (0.40)
SCHEMBL18858531 0.71 NOS3 (0.46)
SCHEMBL28225950 0.70 LMNA (0.39) PDE2APDE8APDE5APDE9APDE6A
SCHEMBL16680007 0.69 MAPK1 (0.36)
SCHEMBL4047122 0.69 KCNH2 (0.46) HTR7PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed