Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157 | 0.77 | CACNA1H (0.33) | HCAR2CACNA1H | |
| SCHEMBL13680917 | 0.73 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL28814422 | 0.70 | — | — | |
| SCHEMBL13680913 | 0.69 | — | — | |
| SCHEMBL21095905 | 0.69 | HTT (0.31) | — | |
| SCHEMBL9020936 | 0.68 | TAAR1 (0.36) | — | |
| SCHEMBL4711556 | 0.66 | ALDH1A1 (0.31) | — | |
| SCHEMBL3286058 | 0.64 | BACE1 (0.36) | — | |
| SCHEMBL28295612 | 0.64 | NOS3 (0.41) | — | |
| SCHEMBL13680925 | 0.64 | POLB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492787-A2 | (CONDENSED) PYRIMIDONE AND (CONDENSED) PYRIDONE COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003087088-A2 | (CONDENSED) PYRIMIDONE AND (CONDENSED) PYRIDONE COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 2003-10-23 | — | — | WO | disclosed |