Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CTSD | P07339 | 5/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572119 | 0.88 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL28668958 | 0.84 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL28074773 | 0.83 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL636601 | 0.83 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL27610152 | 0.80 | SMN1; SMN2 (0.51) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL27512815 | 0.78 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL29976361 | 0.78 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL67755 | 0.78 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL66837 | 0.78 | ALDH1A1 (0.56) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL14705131 | 0.78 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2618821-A2 | NANOSTRUCTURED GELS CAPABLE OF CONTROLLED RELEASE OF ENCAPSULATED AGENTS | The Brigham and Women's Hospital, Inc. (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012040623-A2 | NANOSTRUCTURED GELS CAPABLE OF CONTROLLED RELEASE OF ENCAPSULATED AGENTS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-03-29 | — | — | WO | disclosed |