Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | PPID | Q08752 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593906 | 1.00 | USP2 (0.50) | USP2PPIDTAS1R3TAS1R1L3MBTL1 | |
| SCHEMBL9595916 | 0.88 | USP2 (0.39) | USP2PPIDL3MBTL1POLBKMT2A | |
| SCHEMBL8744728 | 0.88 | USP2 (0.39) | USP2PPIDL3MBTL1POLBKMT2A | |
| SCHEMBL8744841 | 0.85 | MEN1 (0.51) | USP2KMT2AMEN1MAPK1 | |
| SCHEMBL8744835 | 0.85 | MEN1 (0.51) | USP2KMT2AMEN1MAPK1 | |
| SCHEMBL8744707 | 0.81 | LMNA (0.51) | USP2PPIDTAS1R3TAS1R1L3MBTL1 | |
| SCHEMBL9595460 | 0.81 | LMNA (0.51) | USP2PPIDTAS1R3TAS1R1L3MBTL1 | |
| SCHEMBL8744806 | 0.80 | TAS1R3 (0.50) | PPIDTAS1R3TAS1R1L3MBTL1POLB | |
| SCHEMBL9593287 | 0.80 | TAS1R3 (0.50) | PPIDTAS1R3TAS1R1L3MBTL1POLB | |
| SCHEMBL2330760 | 0.80 | PPID (0.55) | PPIDL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456063-B1 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5258527-A | Insecticidal, acaricidal and herbicidal 1-H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-02 | — | — | US | disclosed |
| EP-0456063-A2 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1991-11-13 | — | — | EP | disclosed |