Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9594665 | 1.00 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1EPHX2ITGB1ITGA4 | |
| SCHEMBL8744826 | 0.89 | ITGB1 (0.54) | ALDH1A1L3MBTL1ITGB1ITGA4LDHA | |
| SCHEMBL8744821 | 0.89 | ITGB1 (0.54) | ALDH1A1L3MBTL1ITGB1ITGA4LDHA | |
| SCHEMBL8744805 | 0.88 | TACR1 (0.57) | ALDH1A1L3MBTL1TACR1KMT2ATP53 | |
| SCHEMBL9594563 | 0.88 | TACR1 (0.57) | ALDH1A1L3MBTL1TACR1KMT2ATP53 | |
| SCHEMBL11674845 | 0.82 | ACACB (0.54) | ALDH1A1EPHX2TACR1LDHAGLA | |
| SCHEMBL14370512 | 0.82 | ACACB (0.54) | ALDH1A1EPHX2TACR1LDHAGLA | |
| SCHEMBL4403600 | 0.79 | ALDH1A1 (0.55) | ALDH1A1GLAKMT2AHDAC3HDAC4 | |
| SCHEMBL26148921 | 0.79 | GAA (0.54) | ALDH1A1EPHX2GAARAB9A | |
| SCHEMBL28356496 | 0.79 | HDAC8 (0.60) | ALDH1A1KMT2AHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456063-B1 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5258527-A | Insecticidal, acaricidal and herbicidal 1-H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-02 | — | — | US | disclosed |