Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9594563 | 1.00 | TACR1 (0.57) | TACR1TP53POLBALDH1A1GAA | |
| SCHEMBL8744788 | 0.88 | L3MBTL1 (0.57) | TACR1L3MBTL1CTSLCTSBCTSS | |
| SCHEMBL8744782 | 0.88 | L3MBTL1 (0.57) | TACR1L3MBTL1CTSLCTSBCTSS | |
| SCHEMBL11559927 | 0.88 | TP53 (0.60) | TACR1TP53POLBALDH1A1GAA | |
| SCHEMBL8744831 | 0.88 | ALDH1A1 (0.50) | TACR1TP53ALDH1A1GAARAB9A | |
| SCHEMBL9594665 | 0.88 | ALDH1A1 (0.50) | TACR1TP53ALDH1A1GAARAB9A | |
| SCHEMBL9594200 | 0.86 | ELANE (0.48) | TACR1TP53MEN1KMT2A | |
| SCHEMBL8744711 | 0.86 | ELANE (0.48) | TACR1TP53MEN1KMT2A | |
| SCHEMBL9487298 | 0.84 | TP53 (0.61) | TACR1TP53POLBALDH1A1GAA | |
| SCHEMBL9487303 | 0.84 | TP53 (0.61) | TACR1TP53POLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456063-B1 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5258527-A | Insecticidal, acaricidal and herbicidal 1-H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-02 | — | — | US | disclosed |
| EP-0456063-A2 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1991-11-13 | — | — | EP | disclosed |