Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.54 |
| ▸ | FPR2 | P25090 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | IL2 | P60568 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744821 | 1.00 | ITGB1 (0.54) | ITGB1ITGA4FPR2KMT2ALDHA | |
| SCHEMBL9594665 | 0.89 | ALDH1A1 (0.50) | ITGB1ITGA4KMT2ALDHAALDH1A1 | |
| SCHEMBL8744831 | 0.89 | ALDH1A1 (0.50) | ITGB1ITGA4KMT2ALDHAALDH1A1 | |
| SCHEMBL8744782 | 0.87 | L3MBTL1 (0.57) | ITGB1ITGA4L3MBTL1ITGB3 | |
| SCHEMBL8744788 | 0.87 | L3MBTL1 (0.57) | ITGB1ITGA4L3MBTL1ITGB3 | |
| SCHEMBL5189503 | 0.82 | FPR2 (0.68) | FPR2KMT2ALDHAALDH1A1ALOX15 | |
| SCHEMBL9790211 | 0.81 | HTT (0.59) | FPR2KMT2ALDHACA2PTPN1 | |
| SCHEMBL9790209 | 0.81 | HTT (0.59) | FPR2KMT2ALDHACA2PTPN1 | |
| SCHEMBL8744805 | 0.79 | TACR1 (0.57) | KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL9594563 | 0.79 | TACR1 (0.57) | KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456063-B1 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |