Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.71 |
| ▸ | RAB9A | P51151 | 8/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.71 |
| ▸ | RELA | Q04206 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.62 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25970319 | 0.92 | KDM4E (0.74) | NPC1RAB9ATP53GAANFKB1 | |
| SCHEMBL3363253 | 0.87 | KDM4E (0.82) | NPC1RAB9ATP53GAANFKB1 | |
| SCHEMBL8744898 | 0.86 | NPC1 (0.56) | NPC1RAB9ATP53GAANFKB1 | |
| SCHEMBL531914 | 0.82 | NPC1 (0.66) | NPC1RAB9ATP53GAANFKB1 | |
| SCHEMBL126415 | 0.79 | PTPN1 (0.87) | NPC1RAB9ASMN1; SMN2KDM4EKCNK3 | |
| SCHEMBL5582622 | 0.78 | NPC1 (0.60) | NPC1RAB9ATP53GAANFKB1 | |
| SCHEMBL7005456 | 0.78 | MAPK14 (0.74) | NPC1RAB9ATP53GAANFKB1 | |
| SCHEMBL14715899 | 0.77 | PTPN1 (0.77) | NPC1RAB9ASMN1; SMN2KDM4EKCNK3 | |
| SCHEMBL2298254 | 0.77 | KCNK3 (1.00) | NPC1RAB9ATP53KCNK3KCNK9 | |
| SCHEMBL19041327 | 0.77 | RAB9A (0.63) | NPC1RAB9ATP53GAANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754693-A2 | Novel aminophenylphosphonic acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-01-22 | — | — | EP | disclosed |