Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 4/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744889 | 0.86 | NPC1 (0.71) | NPC1RAB9ATP53GAANFKB1 | |
| SCHEMBL25970319 | 0.79 | KDM4E (0.74) | NPC1RAB9ATP53GAANFKB1 | |
| SCHEMBL3363253 | 0.78 | KDM4E (0.82) | NPC1RAB9ATP53GAANFKB1 | |
| SCHEMBL20887163 | 0.75 | NPC1 (0.68) | NPC1RAB9ATP53KDM4ELMNA | |
| SCHEMBL11745852 | 0.72 | NPC1 (0.56) | NPC1RAB9ATP53MEN1KMT2A | |
| SCHEMBL531914 | 0.71 | NPC1 (0.66) | NPC1RAB9ATP53GAANFKB1 | |
| SCHEMBL6054998 | 0.71 | L3MBTL1 (0.76) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL28987534 | 0.71 | L3MBTL1 (0.72) | NPC1RAB9ATP53GAANFKB1 | |
| SCHEMBL2298254 | 0.70 | KCNK3 (1.00) | NPC1RAB9ATP53KCNK3KCNK9 | |
| SCHEMBL11900392 | 0.70 | NPC1 (0.71) | NPC1RAB9ATP53SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754693-A2 | Novel aminophenylphosphonic acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-01-22 | — | — | EP | disclosed |