Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901326 | 0.87 | KMT2A (0.68) | KMT2AMAPTL3MBTL1HSD17B10FFAR1 | |
| SCHEMBL8744966 | 0.86 | KDM4E (0.71) | ITGB3ITGA2BKMT2AMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL8745027 | 0.85 | KDM4E (0.70) | ITGB3ITGA2BKMT2AMAPTHSD17B10 | |
| SCHEMBL4539667 | 0.85 | ITGB3 (0.71) | ITGB3ITGA2BL3MBTL1SIGMAR1ALDH1A1 | |
| SCHEMBL10898711 | 0.84 | SIGMAR1 (0.66) | SIGMAR1PKM | |
| SCHEMBL10901064 | 0.83 | ITGB3 (0.70) | ITGB3ITGA2BKMT2AMAPTL3MBTL1 | |
| SCHEMBL5542061 | 0.83 | SIGMAR1 (0.60) | KMT2AMAPTL3MBTL1HSD17B10SIGMAR1 | |
| SCHEMBL5542069 | 0.83 | DRD4 (0.66) | KMT2AMAPTL3MBTL1HSD17B10FFAR1 | |
| SCHEMBL11923385 | 0.83 | SIGMAR1 (0.79) | KMT2AMAPTL3MBTL1HSD17B10SIGMAR1 | |
| SCHEMBL8691440 | 0.83 | DRD4 (0.70) | ITGB3ITGA2BMAPTGFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | claimed |
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |