Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3701444 | 0.81 | HTR2A (0.40) | GPR3HTR2ACYP1A2CYP2D6HDAC3 | |
| SCHEMBL4634572 | 0.78 | GPR3 (0.38) | GPR3HTR2A | |
| SCHEMBL7840975 | 0.78 | KMT2A (0.35) | GPR3HTR2ACYP2D6HDAC3HDAC4 | |
| SCHEMBL6424856 | 0.78 | HTR2A (0.38) | GPR3HTR2A | |
| SCHEMBL14744180 | 0.75 | HTR2A (0.39) | GPR3HTR2AHDAC3HDAC4HDAC7 | |
| SCHEMBL215606 | 0.75 | LMNA (0.39) | GPR3HTR2ACYP1A2CYP19A1 | |
| SCHEMBL1107108 | 0.74 | GPR3 (0.48) | GPR3HTR2ACYP1A2CYP2D6CYP19A1 | |
| SCHEMBL6306483 | 0.73 | HTR2A (0.42) | GPR3HTR2A | |
| SCHEMBL6310076 | 0.73 | POLB (0.35) | GPR3HTR2ACYP1A2 | |
| SCHEMBL9422237 | 0.73 | GPR3 (0.34) | GPR3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754693-A2 | Novel aminophenylphosphonic acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-01-22 | — | — | EP | disclosed |