Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3701444 | 0.79 | HTR2A (0.40) | CYP2D6HDAC3HDAC4HDAC7HDAC8 | |
| SCHEMBL8744967 | 0.78 | GPR3 (0.34) | CYP2D6HDAC3HDAC4HDAC7HDAC8 | |
| SCHEMBL6424856 | 0.76 | HTR2A (0.38) | HTR2BHTR7GPR3HTR2A | |
| SCHEMBL4634572 | 0.76 | GPR3 (0.38) | KMT2AMEN1HTR2BHTR7GPR3 | |
| SCHEMBL29884836 | 0.75 | MAOA (0.52) | KMT2AKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL216862 | 0.75 | MAOA (0.52) | KMT2AKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL29376368 | 0.75 | MAOA (0.52) | KMT2AKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL28912100 | 0.74 | HDAC3 (0.44) | KMT2AMEN1MAPTHDAC3HDAC4 | |
| SCHEMBL14744180 | 0.73 | HTR2A (0.39) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL215606 | 0.73 | LMNA (0.39) | ALDH1A1TP53CYP3A4MAPTHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4783387-A | Photosensitive member comprising disazo pigment | MINOLTA CAMERA KABUSHIKI KAISHA (JP) | 1988-11-08 | — | — | US | claimed |
| EP-1144381-A2 | SUBSTITUTED BENZO[DE]ISOQUINOLINE-1,3-DIONES | MERCK PATENT GmbH (DE) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000032577-A2 | SUBSTITUTED BENZO[DE]ISOQUINOLINE-1,3-DIONES | MERCK PATENT GMBH (DE) | 2000-06-08 | — | — | WO | disclosed |
| EP-0754693-A2 | Novel aminophenylphosphonic acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-01-22 | — | — | EP | disclosed |