Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744984 | 0.84 | ATM (0.70) | LMNAALDH1A1SMN1; SMN2ATMITGB3 | |
| SCHEMBL2650203 | 0.84 | MEN1 (0.71) | HTTLMNATSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8745009 | 0.83 | ATM (0.68) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL18177866 | 0.79 | MEN1 (0.60) | HTTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL5775668 | 0.77 | MAPT (0.53) | LMNATSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL3436288 | 0.77 | ALDH1A1 (0.46) | HTTTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL15937763 | 0.74 | DRD4 (0.62) | HTTLMNAMEN1KMT2ATP53 | |
| SCHEMBL5304957 | 0.74 | MC4R (0.62) | LMNAALDH1A1SMN1; SMN2TP53ITGB3 | |
| SCHEMBL3436302 | 0.74 | TSHR (0.66) | HTTLMNATSHRMEN1KMT2A | |
| SCHEMBL5772886 | 0.74 | LMNA (0.69) | HTTLMNATSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | claimed |
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |