Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745034 | 0.88 | ATM (0.58) | ATMHDAC1HDAC4KCNH2MEN1 | |
| SCHEMBL8690003 | 0.88 | ATM (0.67) | ATMHDAC1HDAC4KCNH2MEN1 | |
| Hydrochloric Acid SCHEMBL8744980 | 0.87 | ATM (0.57) | ATMHDAC1HDAC4KCNH2MEN1 | |
| SCHEMBL8744968 | 0.83 | HRH1 (0.64) | ATMHDAC1HDAC4KCNH2MEN1 | |
| SCHEMBL8692759 | 0.76 | KMT2A (0.59) | MEN1KMT2AOPRD1FNTAFNTB | |
| Hydrochloric Acid SCHEMBL8693837 | 0.75 | KMT2A (0.61) | MEN1KMT2AOPRD1FNTAFNTB | |
| SCHEMBL8691241 | 0.75 | ATM (0.76) | ATMHDAC1HDAC4KCNH2MEN1 | |
| SCHEMBL7181030 | 0.74 | LMNA (0.55) | ATMKCNH2OPRD1FNTAFNTB | |
| SCHEMBL7952124 | 0.73 | OPRD1 (0.54) | MEN1KMT2AOPRD1OPRK1OPRM1 | |
| SCHEMBL7364364 | 0.72 | DRD4 (0.59) | HDAC1HDAC4MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | claimed |
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |