Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.64 |
| ▸ | CNR1 | P21554 | 2/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.64 |
| ▸ | GHSR | Q92847 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.59 |
| ▸ | HRH2 | P25021 | 2/20 | 0.59 |
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | DRD3 | P35462 | 2/20 | 0.59 |
| ▸ | HTR2B | P41595 | 2/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690003 | 0.94 | ATM (0.67) | HRH1KCNH2ADORA3CNR1OPRK1 | |
| SCHEMBL8744969 | 0.87 | ATM (0.67) | HRH1KCNH2ADORA3CNR1OPRK1 | |
| SCHEMBL12464946 | 0.84 | KCNH2 (0.80) | HRH1KCNH2ADORA3CNR1OPRK1 | |
| SCHEMBL8744992 | 0.83 | ATM (0.53) | HRH1KCNH2ADORA3CNR1OPRK1 | |
| SCHEMBL1569388 | 0.82 | KCNH2 (0.70) | HRH1KCNH2ADORA3CNR1OPRK1 | |
| SCHEMBL588111 | 0.82 | KCNH2 (0.78) | HRH1KCNH2ADORA3CNR1OPRK1 | |
| SCHEMBL588110 | 0.82 | KCNH2 (0.78) | HRH1KCNH2ADORA3CNR1OPRK1 | |
| SCHEMBL3611802 | 0.82 | KCNH2 (0.78) | HRH1KCNH2ADORA3CNR1OPRK1 | |
| SCHEMBL9720751 | 0.81 | KCNH2 (0.71) | HRH1KCNH2ADORA3CNR1OPRK1 | |
| SCHEMBL8691241 | 0.81 | ATM (0.76) | HRH1KCNH2ADORA3CNR1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | claimed |
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |