Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454046 | 0.82 | KCNH2 (0.46) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL27589246 | 0.79 | KCNH2 (0.50) | MAOBLMNAGAAMAPTRAB9A | |
| SCHEMBL27413501 | 0.79 | MAOB (0.43) | MAOBBCHECYP1A2CYP2C19APP | |
| SCHEMBL27953764 | 0.75 | RXRA (0.43) | GAAMAPTRAB9AL3MBTL1 | |
| SCHEMBL27525209 | 0.75 | MAOB (0.51) | MAOBBCHELMNACYP1A2PTGS1 | |
| SCHEMBL10607034 | 0.74 | LMNA (0.64) | MAOBBCHELMNACYP1A2PTGS1 | |
| SCHEMBL10650830 | 0.71 | SMN1; SMN2 (0.50) | LMNAPTGS1SLC6A2SLC6A3HIF1A | |
| SCHEMBL7785326 | 0.70 | NQO1 (0.47) | LMNACYP1A2CYP2C19GAAMAPT | |
| SCHEMBL7634483 | 0.69 | TSHR (0.40) | — | |
| SCHEMBL6736549 | 0.69 | TDP1 (0.47) | MAOBAPPL3MBTL1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466220-B1 | Carboxy containing monomers and polymers and latices prepared from same | JOHNSON & JOHNSON CLIN DIAG (US) | 1997-01-29 | — | — | EP | claimed |
| EP-0466220-B1 | Carboxy containing monomers and polymers and latices prepared from same | JOHNSON & JOHNSON CLIN DIAG (US) | 1997-01-29 | — | — | EP | disclosed |