Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745155 | 0.96 | TRPA1 (0.34) | TRPA1TUBB1FYN | |
| SCHEMBL8745288 | 0.92 | TRPA1 (0.32) | TRPA1TUBB1 | |
| SCHEMBL8745188 | 0.91 | PKM (0.30) | TRPA1 | |
| SCHEMBL7911272 | 0.87 | TLR4 (0.33) | TLR4FYN | |
| SCHEMBL7911280 | 0.87 | TLR4 (0.33) | TLR4FYN | |
| SCHEMBL7911274 | 0.87 | TLR4 (0.33) | TLR4FYN | |
| SCHEMBL7911283 | 0.87 | TLR4 (0.33) | TLR4FYN | |
| SCHEMBL8745643 | 0.87 | TRPA1 (0.34) | TRPA1TUBB1 | |
| SCHEMBL8745169 | 0.86 | NFE2L2 (0.39) | TLR4TRPA1 | |
| SCHEMBL8745171 | 0.86 | PKM (0.32) | TRPA1TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5401434-A | Cis-1,4-substituted 2-butene derivative | CHISSO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0563981-A2 | Cis-1,4-substituted 2-butene derivative | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |