Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747230 | 0.96 | MAOA (0.39) | MAOBMAOATNNC1ITGB3ITGA2B | |
| SCHEMBL8745290 | 0.93 | MAOB (0.43) | MAOBMAOATNNC1ITGB3ITGA2B | |
| SCHEMBL8745621 | 0.90 | TNNC1 (0.47) | TNNC1HTR2AHTR2CLPLLIPG | |
| SCHEMBL8745253 | 0.89 | MAOA (0.40) | MAOBMAOATNNC1ITGB3ITGA2B | |
| SCHEMBL8745255 | 0.89 | TNNC1 (0.48) | MAOBMAOATNNC1ITGB3ITGA2B | |
| SCHEMBL8745292 | 0.88 | ALOX5 (0.37) | MAOBMAOATNNC1ITGB3ITGA2B | |
| SCHEMBL8745277 | 0.87 | TNNC1 (0.44) | TNNC1HTR2AHTR2CKDM4EALDH1A1 | |
| SCHEMBL8745203 | 0.85 | TNNC1 (0.45) | MAOBMAOATNNC1ITGB3ITGA2B | |
| SCHEMBL8745334 | 0.84 | ALOX5 (0.35) | TNNC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8747219 | 0.83 | TNNC1 (0.48) | TNNC1HTR2AHTR2CLPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5401434-A | Cis-1,4-substituted 2-butene derivative | CHISSO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0563981-A2 | Cis-1,4-substituted 2-butene derivative | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |