Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139133 | 0.96 | GRIK1 (0.37) | GRIK1GRIK2KDM1ARCOR1HRH3 | |
| SCHEMBL8745246 | 0.92 | GRIK1 (0.39) | GRIK1GRIK2KDM1ARCOR1HRH3 | |
| SCHEMBL9137050 | 0.88 | GRIK1 (0.37) | GRIK1GRIK2KDM1ARCOR1HRH3 | |
| SCHEMBL8745269 | 0.88 | GRIK1 (0.37) | GRIK1GRIK2KDM1ARCOR1HRH3 | |
| SCHEMBL8745248 | 0.85 | GRIK1 (0.35) | GRIK1GRIK2KDM1ARCOR1HRH3 | |
| SCHEMBL8745216 | 0.82 | MAOB (0.41) | HTR2A | |
| SCHEMBL8745185 | 0.81 | NFE2L2 (0.38) | SLC6A4SLC6A3HTR2A | |
| SCHEMBL8745292 | 0.81 | ALOX5 (0.37) | ALDH1A1PIM1PIM2 | |
| SCHEMBL15933248 | 0.79 | GRIK1 (0.46) | GRIK1GRIK2KDM1ARCOR1ALDH1A1 | |
| SCHEMBL27616402 | 0.79 | GRIK1 (0.48) | GRIK1GRIK2KDM1ARCOR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5401434-A | Cis-1,4-substituted 2-butene derivative | CHISSO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0563981-A2 | Cis-1,4-substituted 2-butene derivative | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |