SCHEMBL8745392

SCHEMBL8745392

O=S(=O)(c1ccccc1O)c1ccccc1OCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.47
ALPG P10696 1/20 0.46
PTK2B Q14289 1/20 0.46
HTR1A P08908 2/20 0.46
ADRA1D P25100 1/20 0.46
ADRA1A P35348 1/20 0.46
ADRA1B P35368 1/20 0.46
SGMS2 Q8NHU3 2/20 0.46
LIPE Q05469 1/20 0.45
MAPT P10636 1/20 0.45
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
MCL1 Q07820 1/20 0.44
ACLY P53396 1/20 0.43
BRD4 O60885 1/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA9 Q16790 2/20 0.43
CA12 O43570 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7108877 0.90 MAPT (0.53) ALPGPTK2BHTR1AADRA1DADRA1A
SCHEMBL8745396 0.83 TSHR (0.54) ALPGMAPTMAPK1TDP1L3MBTL1
SCHEMBL7751043 0.83 HTR6 (0.49) ALPGPTK2BLIPEMAPTMAPK1
SCHEMBL7172816 0.81 MAPT (0.46) MAPTMAPK1L3MBTL1CA1CA2
SCHEMBL10600672 0.81 CYP1A2 (0.43) ALPGPTK2BMCL1ACLYCA1
SCHEMBL1028419 0.80 ALPG (0.51) ALPGPTK2BHTR1ASGMS2LIPE
SCHEMBL1013565 0.80 CA1 (0.56) ALPGPTK2BHTR1AADRA1DADRA1A
SCHEMBL1791707 0.80 APP (0.42) APPMAPTCA1CA2CA9
SCHEMBL28291811 0.79 CA12 (0.63) CA1CA2CA9CA12CA4
SCHEMBL10344838 0.78 MAOB (0.48) ALPGPTK2BLIPEMCL1ACLY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0416684-B1 Photographic yellow couplers, method for their preparation and intermediates therefor EASTMAN KODAK CO (US) 1997-01-29 EP disclosed
US-5021333-A Pivaloylacetanilide-type yellow coupler EASTMAN KODAK COMPANY (US) 1991-06-04 US disclosed
EP-0416684-A2 Photographic yellow couplers, method for their preparation and intermediates therefor EASTMAN KODAK COMPANY (US) 1991-03-13 EP disclosed