Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 8/20 | 0.55 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | THRA | P10827 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28094930 | 1.00 | PCNA (0.55) | PCNATACR1ALDH1A1THRBLMNA | |
| SCHEMBL28680811 | 0.91 | PCNA (0.67) | PCNATACR1THRBLMNAMEN1 | |
| SCHEMBL28680813 | 0.91 | PCNA (0.67) | PCNATACR1THRBLMNAMEN1 | |
| SCHEMBL7631233 | 0.87 | TACR1 (0.43) | PCNATACR1ALDH1A1MEN1KMT2A | |
| SCHEMBL6723723 | 0.86 | THRB (0.58) | PCNATACR1ALDH1A1THRBLMNA | |
| SCHEMBL6723726 | 0.86 | THRB (0.58) | PCNATACR1ALDH1A1THRBLMNA | |
| SCHEMBL30592753 | 0.85 | ACACB (0.51) | TACR1ALDH1A1KMT2A | |
| SCHEMBL8745407 | 0.84 | PCNA (0.59) | PCNAALDH1A1THRBLMNAMEN1 | |
| SCHEMBL14370512 | 0.83 | ACACB (0.54) | TACR1ALDH1A1KMT2A | |
| SCHEMBL11674845 | 0.83 | ACACB (0.54) | TACR1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116715597-B | Production process of levothyroxine sodium | 湖北潜龙药业有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-116715597-A | Production process of levothyroxine sodium | 湖北潜龙药业有限公司 | 2023-09-08 | — | — | CN | claimed |
| CN-109761830-B | Preparation method of levothyroxine sodium | 珐玛赫(天津)科技有限公司 | 2021-12-17 | — | — | CN | claimed |
| CN-116715597-B | Production process of levothyroxine sodium | 湖北潜龙药业有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-116715597-B | Production process of levothyroxine sodium | 湖北潜龙药业有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-116715597-A | Production process of levothyroxine sodium | 湖北潜龙药业有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-116715597-A | Production process of levothyroxine sodium | 湖北潜龙药业有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-109761830-B | Preparation method of levothyroxine sodium | 珐玛赫(天津)科技有限公司 | 2021-12-17 | — | — | CN | disclosed |
| CN-109761830-B | Preparation method of levothyroxine sodium | 珐玛赫(天津)科技有限公司 | 2021-12-17 | — | — | CN | disclosed |
| EP-3024326-B1 | NOVEL PROCESS FOR THE PREPARATION OF LEVOTHYROXINE SODIUM | AZICO BIOPHORE INDIA PRIVATE LTD (IN) | 2018-12-12 | — | — | EP | disclosed |
| US-9428444-B2 | Process for the preparation of levothyroxine sodium | AZICO BIOPHORE INDIA PRIVATE LIMITED (IN) | 2016-08-30 | — | — | US | disclosed |
| US-20160168076-A1 | NOVEL PROCESS FOR THE PREPARATION OF LEVOTHYROXINE SODIUM | AZICO BIOPHORE INDIA PRIVATE LIMITED (IN) | 2016-06-16 | — | — | US | disclosed |
| EP-3024326-A1 | NOVEL PROCESS FOR THE PREPARATION OF LEVOTHYROXINE SODIUM | Azico Biophore India Private Limited (IN) | 2016-06-01 | — | — | EP | disclosed |
| WO-2015011573-A1 | NOVEL PROCESS FOR THE PREPARATION OF LEVOTHYROXINE SODIUM | AZICO PHARMACEUTICALS PRIVATE LIMITED (IN) | 2015-01-29 | — | — | WO | disclosed |
| EP-0612308-B1 | METHOD FOR PREPARING RADIO-IODINATED THYRONINE DERIVATIVES; NOVEL INTERMEDIATES | HENNING BERLIN GMBH (DE) | 1997-02-05 | — | — | EP | disclosed |
| EP-0612308-A1 | METHOD FOR PREPARING RADIO-IODINATED THYRONINE DERIVATIVES; NOVEL INTERMEDIATES. | HENNING BERLIN GMBH (DE) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993009076-A1 | METHOD FOR PREPARING RADIO-IODINATED THYRONINE DERIVATIVES; NOVEL INTERMEDIATES | HENNING BERLIN GMBH CHEMIE- UND PHARMAWERK (DE) | 1993-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168076-A1 | NOVEL PROCESS FOR THE PREPARATION OF LEVOTHYROXINE SODIUM | TPO, TH, TYR | PCNA 2907/4885TACR1 1336/4885ALDH1A1 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.