Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 14/20 | 0.51 |
| ▸ | THRB | P10828 | 14/20 | 0.51 |
| ▸ | PCNA | P12004 | 4/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21598075 | 0.83 | FOLH1 (0.52) | PPARG | |
| SCHEMBL21598076 | 0.83 | FOLH1 (0.52) | PPARG | |
| SCHEMBL8745418 | 0.81 | PCNA (0.72) | THRATHRBPCNAPPARG | |
| SCHEMBL7630334 | 0.81 | PCNA (0.72) | THRATHRBPCNAPPARG | |
| SCHEMBL3961476 | 0.80 | HPGD (0.41) | THRATHRBPPARG | |
| SCHEMBL8745433 | 0.78 | KMT2A (0.48) | THRATHRBPPARG | |
| SCHEMBL8745406 | 0.78 | KMT2A (0.48) | THRATHRBPPARG | |
| SCHEMBL8745435 | 0.77 | THRA (0.48) | THRATHRBPCNAPPARG | |
| SCHEMBL161943 | 0.76 | FOLH1 (0.60) | — | |
| SCHEMBL160418 | 0.76 | FOLH1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612308-B1 | METHOD FOR PREPARING RADIO-IODINATED THYRONINE DERIVATIVES; NOVEL INTERMEDIATES | HENNING BERLIN GMBH (DE) | 1997-02-05 | — | — | EP | disclosed |
| EP-0612308-A1 | METHOD FOR PREPARING RADIO-IODINATED THYRONINE DERIVATIVES; NOVEL INTERMEDIATES. | HENNING BERLIN GMBH (DE) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993009076-A1 | METHOD FOR PREPARING RADIO-IODINATED THYRONINE DERIVATIVES; NOVEL INTERMEDIATES | HENNING BERLIN GMBH CHEMIE- UND PHARMAWERK (DE) | 1993-05-13 | — | — | WO | disclosed |