Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 8/20 | 0.47 |
| ▸ | THRB | P10828 | 8/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745433 | 1.00 | KMT2A (0.48) | KMT2AFPR2THRATHRBCA2 | |
| SCHEMBL8745430 | 0.91 | PCNA (0.42) | THRATHRB | |
| SCHEMBL8745450 | 0.86 | KMT2A (0.45) | KMT2AFPR2THRATHRBCA2 | |
| SCHEMBL8745468 | 0.86 | FPR2 (0.49) | KMT2AFPR2CA2ITGB3ITGA2B | |
| SCHEMBL27850539 | 0.83 | ITGB3 (0.60) | KMT2AFPR2CA2ITGB3ITGA2B | |
| SCHEMBL27850537 | 0.83 | ITGB3 (0.60) | KMT2AFPR2CA2ITGB3ITGA2B | |
| SCHEMBL8745457 | 0.83 | THRB (0.61) | KMT2ATHRATHRBALDH1A1ALOX15 | |
| SCHEMBL4361126 | 0.82 | ITGB3 (0.64) | KMT2AFPR2CA2ITGB3ITGA2B | |
| SCHEMBL6438360 | 0.82 | ITGB3 (0.64) | KMT2AFPR2CA2ITGB3ITGA2B | |
| SCHEMBL10660397 | 0.82 | ITGB3 (0.64) | KMT2AFPR2CA2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612308-B1 | METHOD FOR PREPARING RADIO-IODINATED THYRONINE DERIVATIVES; NOVEL INTERMEDIATES | HENNING BERLIN GMBH (DE) | 1997-02-05 | — | — | EP | claimed |