Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14255285 | 0.86 | ALDH1A1 (0.61) | CA2ALDH1A1PLCG1MMP2CA12 | |
| SCHEMBL5403737 | 0.85 | CA2 (0.54) | CA2ALDH1A1PLCG1MMP2CA12 | |
| SCHEMBL31713539 | 0.82 | CA2 (0.46) | CA2ALDH1A1PLCG1MMP2CA12 | |
| SCHEMBL4932324 | 0.79 | PLCG1 (0.47) | CA2ALDH1A1PLCG1MMP2CA12 | |
| SCHEMBL16098137 | 0.79 | CA2 (0.43) | CA2ALDH1A1PLCG1MMP2CA12 | |
| SCHEMBL18084499 | 0.79 | PLCG1 (0.47) | CA2ALDH1A1PLCG1MMP2CA12 | |
| SCHEMBL8745517 | 0.78 | GAA (0.56) | CA2ALDH1A1MMP2CA12CA9 | |
| SCHEMBL714645 | 0.76 | CA2 (0.50) | CA2ALDH1A1PLCG1MMP2CA12 | |
| SCHEMBL24590292 | 0.76 | PLCG1 (0.44) | CA2ALDH1A1PLCG1MMP2CA12 | |
| SCHEMBL13625364 | 0.76 | CA2 (0.41) | CA2ALDH1A1PLCG1MMP2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654149-B1 | POSITIVE-ACTING RADIATION-SENSITIVE MIXTURE AND RECORDING MATERIAL PRODUCED THEREWITH | HOECHST AG (DE) | 1997-02-05 | — | — | EP | disclosed |
| EP-0654149-A1 | POSITIVE-ACTING RADIATION-SENSITIVE MIXTURE AND RECORDING MATERIAL PRODUCED THEREWITH. | HOECHST AG (DE) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994003837-A1 | POSITIVE-ACTING RADIATION-SENSITIVE MIXTURE AND RECORDING MATERIAL PRODUCED THEREWITH | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-17 | — | — | WO | disclosed |