Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 8/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL515135 | 0.87 | FDPS (0.43) | FDPSLPAR3LPAR2MMP1MMP2 | |
| Butane SCHEMBL1502269 | 0.87 | — | — | |
| Butane SCHEMBL11127801 | 0.81 | — | — | |
| Alcohol SCHEMBL6239128 | 0.74 | ALDH1A1 (0.46) | FDPSLPAR3LPAR2MMP1MMP2 | |
| Phosphoric Acid SCHEMBL6827845 | 0.73 | FDPS (0.47) | FDPSLPAR3LPAR2MMP1MMP2 | |
| Phosphoric Acid SCHEMBL15540528 | 0.73 | FDPS (0.47) | FDPSLPAR3LPAR2MMP1MMP2 | |
| Phosphoric Acid SCHEMBL10935355 | 0.73 | FDPS (0.47) | FDPSLPAR3LPAR2MMP1MMP2 | |
| Phosphoric Acid SCHEMBL9588189 | 0.73 | FDPS (0.47) | FDPSLPAR3LPAR2MMP1MMP2 | |
| Phosphoric Acid SCHEMBL21081718 | 0.73 | FDPS (0.47) | FDPSLPAR3LPAR2MMP1MMP2 | |
| Phosphoric Acid SCHEMBL337762 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671917-A4 | METHOD FOR INHIBITION OF CELL MOTILITY BY SPHINGOSINE-1-PHOSPHATE, ITS DERIVATIVES AND MIMETICS AND METHOD OF SYNTHESIZING SPHINGOSINE-1-PHOSPHATE AND ITS DERIVATIVES. | BIOMEMBRANE INST (US) | 1997-06-18 | — | — | EP | claimed |
| EP-0671917-A1 | METHOD FOR INHIBITION OF CELL MOTILITY BY SPHINGOSINE-1-PHOSPHATE, ITS DERIVATIVES AND MIMETICS AND METHOD OF SYNTHESIZING SPHINGOSINE-1-PHOSPHATE AND ITS DERIVATIVES | ONCOMEMBRANE, INC. (US) | 1995-09-20 | — | — | EP | claimed |
| WO-1993019760-A1 | METHOD FOR INHIBITION OF CELL MOTILITY BY SPHINGOSINE-1-PHOSPHATE, ITS DERIVATIVES AND MIMETICS AND METHOD OF SYNTHESIZING SPHINGOSINE-1-PHOSPHATE AND ITS DERIVATIVES | THE BIOMEMBRANE INSTITUTE (US) | 1993-10-14 | — | — | WO | claimed |