Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 known ✓ | P03956 | 2/20 | 0.35 |
| ▸ | MMP8 known ✓ | P22894 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 5/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL1502269 | 0.85 | — | — | |
| Butane SCHEMBL515135 | 0.85 | FDPS (0.43) | CA2FDPSLAP3MMP2LPAR3 | |
| Phosphoric Acid SCHEMBL9391422 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TSHRCA2PPARDFDPS | |
| Phosphoric Acid SCHEMBL1686181 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TSHRCA2PPARDFDPS | |
| Phosphoric Acid SCHEMBL173991 | 0.84 | — | — | |
| Phosphoric Acid SCHEMBL28713229 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TSHRCA2PPARDFDPS | |
| Phosphoric Acid SCHEMBL27521724 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TSHRCA2PPARDFDPS | |
| Phosphoric Acid SCHEMBL10887747 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRCA2PPARDFDPS | |
| Phosphoric Acid SCHEMBL10887793 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRCA2PPARDFDPS | |
| Phosphoric Acid SCHEMBL16666217 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRCA2PPARDFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265906-B1 | FLUORINATED LUBRICANT ADDITIVES | DU PONT (US) | 2005-06-22 | — | — | EP | disclosed |
| US-6764984-B2 | CONTAINING FLUORINATION DITHIOPHOSPHONATE SALT | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-07-20 | — | — | US | disclosed |
| US-20030139300-A1 | Fluorinated lubricant additives | BEATTY RICHARD P (US) | 2003-07-24 | — | — | US | disclosed |
| US-6541430-B1 | Wear and friction resistance | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-04-01 | — | — | US | disclosed |
| EP-1265906-A1 | FLUORINATED LUBRICANT ADDITIVES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001072759-A1 | FLUORINATED LUBRICANT ADDITIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139300-A1 | Fluorinated lubricant additives | DSG1, FLNA, DGKI | MMP1 3873/4885MMP8 3737/4885ALDH1A1 695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.