Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | BID | P55957 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96897 | 0.86 | LIPG (0.43) | LIPGNR1H2NR1H3BIDMCL1 | |
| SCHEMBL910303 | 0.86 | GABRA1 (0.41) | LIPGPPARAPPARG | |
| SCHEMBL910690 | 0.84 | GABRA1 (0.47) | — | |
| SCHEMBL30037094 | 0.83 | LIPG (0.65) | LIPGNR1H2NR1H3BIDMCL1 | |
| SCHEMBL82794 | 0.83 | LIPG (0.65) | LIPGNR1H2NR1H3BIDMCL1 | |
| SCHEMBL1372464 | 0.81 | LIPG (0.59) | LIPGNR1H2NR1H3BIDMCL1 | |
| SCHEMBL18496530 | 0.81 | LIPG (0.69) | LIPGNR1H2NR1H3BIDMCL1 | |
| SCHEMBL1343771 | 0.81 | LIPG (0.69) | LIPGNR1H2NR1H3BIDMCL1 | |
| SCHEMBL10980560 | 0.81 | LIPG (0.69) | LIPGNR1H2NR1H3BIDMCL1 | |
| SCHEMBL15809821 | 0.81 | LIPG (0.69) | LIPGNR1H2NR1H3BIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336230-B1 | Cyclic peptide antagonists of Substance P and Substance K | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-02-12 | — | — | EP | claimed |
| EP-0498069-B1 | New use of peptide derivative | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-25 | — | — | EP | claimed |
| US-5217952-A | Analgesics, antihistamine | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-08 | — | — | US | claimed |
| EP-0498069-A2 | New use of peptide derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-12 | — | — | EP | claimed |
| EP-0336230-A2 | Cyclic peptide antagonists of Substance P and Substance K | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-10-11 | — | — | EP | claimed |
| JP-5078254-A | — | — | None | — | — | JP | disclosed |
| EP-0336230-B1 | Cyclic peptide antagonists of Substance P and Substance K | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-02-12 | — | — | EP | disclosed |
| EP-0498069-B1 | New use of peptide derivative | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-25 | — | — | EP | disclosed |
| JP-H0578254-A | ANTIINFLAMMATORY AGENT OR REGULATOR FOR MOTILITY OF DIGESTIVE TRACT | FUJISAWA PHARMACEUT CO LTD | 1993-03-30 | — | — | JP | disclosed |
| EP-0336230-A2 | Cyclic peptide antagonists of Substance P and Substance K | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-10-11 | — | — | EP | disclosed |