SCHEMBL8745709

SCHEMBL8745709

O=CC1(c2ccccc2)CCc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HDAC9 Q9UKV0 1/20 0.46
KDM1A O60341 3/20 0.40
MAOB P27338 1/20 0.40
TSHR P16473 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
HCAR2 Q8TDS4 1/20 0.38
AKR1B1 P15121 1/20 0.37
CYP2C9 P11712 2/20 0.36
SIGMAR1 Q99720 2/20 0.36
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30074626 0.87 HSD11B1 (0.44) HDAC9KDM1AMAOBTSHRTDP1
SCHEMBL8609788 0.82 HDAC9 (0.43) HDAC9KDM1AMAOBTSHRTDP1
SCHEMBL6337745 0.71 HDAC9 (0.49) HDAC9KDM1AMAOBTSHRTDP1
SCHEMBL7445452 0.70 KDM1A (0.46) HDAC9KDM1AMAOBTSHRTDP1
SCHEMBL12305110 0.70 MEN1 (0.44) HDAC9KDM1AMAOBTSHRTDP1
SCHEMBL2465794 0.70 KDM1A (0.46) HDAC9KDM1AMAOBTSHRTDP1
SCHEMBL6267106 0.70 KDM1A (0.53) HDAC9KDM1AMAOBTSHRTDP1
SCHEMBL29784907 0.70 KDM1A (0.53) HDAC9KDM1AMAOBTSHRTDP1
Hydrochloric Acid SCHEMBL29189207 0.69 KDM1A (0.52) HDAC9KDM1AMAOBTSHRTDP1
SCHEMBL133897 0.68 HDAC9 (0.46) HDAC9KDM1AMAOBTSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0487993-B1 Stable liquid compositions useful as polymerization photopromoters, their preparation and use LAMBERTI SPA (IT) 1997-02-05 EP claimed
EP-0487993-A2 Stable liquid compositions useful as polymerization photopromoters, their preparation and use LAMBERTI S.p.A. (IT) 1992-06-03 EP claimed
JP-5132508-A None JP disclosed
EP-0487993-B1 Stable liquid compositions useful as polymerization photopromoters, their preparation and use LAMBERTI SPA (IT) 1997-02-05 EP disclosed
JP-H05132508-A STABLE LIQUID COMPOSITION USEFUL AS PHOTOPOLYMERIZATION ACCELERATOR AND ITS PREPARATION FRATELLI LAMBERTI SPA 1993-05-28 JP disclosed
EP-0487993-A2 Stable liquid compositions useful as polymerization photopromoters, their preparation and use LAMBERTI S.p.A. (IT) 1992-06-03 EP disclosed
EP-0487993-A2 Stable liquid compositions useful as polymerization photopromoters, their preparation and use LAMBERTI S.p.A. (IT) 1992-06-03 EP disclosed
US-4987159-A HIGH EFFICIENCY FRATELLI LAMBERTI S.P.A. (IT) 1991-01-22 US disclosed