Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 6/20 | 0.47 |
| ▸ | GRK6 | P43250 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2 | P10415 | 2/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | PKLR | P30613 | 3/20 | 0.40 |
| ▸ | PGAM1 | P18669 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11107372 | 0.81 | KEAP1 (0.53) | TTRGRK6MEN1MAPTKMT2A | |
| SCHEMBL9316584 | 0.78 | KEAP1 (0.57) | TTRGRK6MEN1MAPTKMT2A | |
| SCHEMBL8745733 | 0.75 | ADORA2A (0.60) | TTRGRK6MEN1MAPTKMT2A | |
| SCHEMBL8777916 | 0.75 | ADORA2A (0.63) | GRK6MEN1MAPTKMT2APOLB | |
| SCHEMBL11432640 | 0.75 | S100A4 (0.43) | TTRMEN1MAPTKMT2APOLB | |
| SCHEMBL11432637 | 0.72 | TTR (0.71) | TTRMEN1MAPTKMT2APOLB | |
| SCHEMBL11247721 | 0.72 | TTR (0.41) | TTRMEN1MAPTKMT2AMCL1 | |
| SCHEMBL10782111 | 0.72 | MCL1 (0.70) | TTRMEN1MAPTKMT2APOLB | |
| SCHEMBL6905214 | 0.71 | TTR (0.64) | TTRMEN1MAPTKMT2APOLB | |
| SCHEMBL26187355 | 0.70 | ELANE (0.69) | TTRMEN1MAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576996-B1 | Method of preparation of 7,16-dichloro-dianthraquinone-N,N'-dihydroazine | BASF AG (DE) | 1997-02-12 | — | — | EP | disclosed |
| EP-0576996-A1 | Method of preparation of 7,16-dichloro-dianthraquinone-N,N'-dihydroazine | BASF Aktiengesellschaft (DE) | 1994-01-05 | — | — | EP | disclosed |