Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.73 |
| ▸ | HPGD | P15428 | 7/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745787 | 0.89 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL8745800 | 0.82 | KDM4E (0.69) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL8745810 | 0.74 | ADRA1A (0.52) | ALDH1A1KDM4E | |
| SCHEMBL703412 | 0.72 | KDM4E (1.00) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL23665718 | 0.71 | ALDH1A1 (0.78) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL8745790 | 0.70 | KDM4E (0.68) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL23665719 | 0.69 | ALDH1A1 (0.74) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL12986819 | 0.69 | KDM4E (0.72) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL12986404 | 0.69 | KDM4E (0.54) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL12987096 | 0.69 | KDM4E (0.54) | ALDH1A1KDM4EHPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663911-B1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | SCHWABE WILLMAR GMBH & CO (DE) | 1997-02-05 | — | — | EP | disclosed |
| US-5550129-A | THERAPY FOR NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | WILLMAR SCHWABE GMBH & CO. (DE) | 1996-08-27 | — | — | US | disclosed |
| EP-0663911-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE. | SCHWABE WILLMAR GMBH & CO (DE) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994008985-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1994-04-28 | — | — | WO | disclosed |