Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745790 | 0.88 | KDM4E (0.68) | KDM4EALDH1A1POLBHTTGAA | |
| SCHEMBL11852795 | 0.83 | KDM4E (0.60) | KDM4EALDH1A1POLBHTTGAA | |
| SCHEMBL8745780 | 0.82 | ALDH1A1 (0.73) | KDM4EALDH1A1POLBHTTGAA | |
| SCHEMBL11835982 | 0.78 | KDM4E (0.53) | KDM4EALDH1A1POLBHTTGAA | |
| SCHEMBL11835976 | 0.76 | KDM4E (0.54) | KDM4EALDH1A1POLBHTTGAA | |
| SCHEMBL8745797 | 0.75 | ALDH1A1 (0.56) | KDM4EALDH1A1POLBHTTGAA | |
| SCHEMBL6755853 | 0.73 | KDM4E (0.62) | KDM4EALDH1A1POLBHTTGAA | |
| SCHEMBL9976086 | 0.71 | ALDH1A1 (0.62) | KDM4EALDH1A1POLBHTTGAA | |
| SCHEMBL9367289 | 0.71 | ALDH1A1 (0.67) | KDM4EALDH1A1POLBHTTGAA | |
| SCHEMBL8745787 | 0.70 | ALDH1A1 (0.71) | KDM4EALDH1A1POLBHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663911-B1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | SCHWABE WILLMAR GMBH & CO (DE) | 1997-02-05 | — | — | EP | disclosed |
| US-5550129-A | THERAPY FOR NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | WILLMAR SCHWABE GMBH & CO. (DE) | 1996-08-27 | — | — | US | disclosed |
| EP-0663911-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE. | SCHWABE WILLMAR GMBH & CO (DE) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994008985-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1994-04-28 | — | — | WO | disclosed |