Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745954 | 0.81 | KDM4E (0.39) | CNR2KDM4EKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL8745946 | 0.78 | KDM4E (0.39) | CNR2KDM4EKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL9028568 | 0.77 | SCN9A (0.37) | CNR2KDM4EKMT2A | |
| SCHEMBL8745915 | 0.77 | CYP3A4 (0.39) | CNR2KDM4EKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL8745950 | 0.76 | CYP3A4 (0.39) | CNR2KDM4EKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL8328825 | 0.74 | SSTR4 (0.38) | KDM4EKMT2ANPSR1 | |
| SCHEMBL8745905 | 0.73 | RBP4 (0.40) | RBP4CNR2KMT2APLK1 | |
| SCHEMBL9028891 | 0.69 | LIMK1 (0.37) | CNR2KDM4EKMT2A | |
| SCHEMBL10217349 | 0.68 | CNR2 (0.41) | CNR2KDM4EKMT2AHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3448575 | 0.67 | POLB (0.40) | CNR2KDM4EKMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |