Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028568 | 0.92 | SCN9A (0.37) | SCN9ACNR2KDM4EKMT2ATYK2 | |
| SCHEMBL9028582 | 0.86 | SCN9A (0.40) | SCN9ACNR2TYK2SLC22A12NOTUM | |
| SCHEMBL9028966 | 0.85 | HPGD (0.36) | SCN9ACNR2TYK2NOTUMALDH1A1 | |
| SCHEMBL9028593 | 0.85 | CNR1 (0.40) | SCN9ACNR2KDM4ETYK2ADAMTS5 | |
| SCHEMBL9028689 | 0.81 | SCN9A (0.37) | SCN9ACNR2TYK2SLC22A12ADAMTS5 | |
| SCHEMBL8549639 | 0.81 | GPBAR1 (0.37) | SCN9ACNR2P2RX7 | |
| SCHEMBL9030025 | 0.80 | GPBAR1 (0.38) | SCN9ATYK2 | |
| SCHEMBL8328825 | 0.77 | SSTR4 (0.38) | KDM4EKMT2ANOTUMALDH1A1POLB | |
| SCHEMBL8550618 | 0.77 | LIPE (0.43) | KDM4EKMT2A | |
| SCHEMBL9028443 | 0.75 | RAB9A (0.34) | SCN9ACNR2TYK2NOTUMADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695292-A1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LIMITED (GB) | 1996-02-07 | — | — | EP | disclosed |