Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.43 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | METAP1 | P53582 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MMP14 | P50281 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27623907 | 0.98 | KDM4E (0.42) | KDM4EMAPTLMNAHSP90AA1METAP2 | |
| SCHEMBL27623901 | 0.98 | KDM4E (0.42) | KDM4EMAPTLMNAHSP90AA1METAP2 | |
| SCHEMBL3956713 | 0.84 | ALDH1A1 (0.38) | KDM4EMAPTLMNAHSP90AA1METAP2 | |
| SCHEMBL5731511 | 0.76 | KMT2A (0.42) | KDM4EMAPTLMNAHSP90AA1L3MBTL1 | |
| SCHEMBL6615818 | 0.76 | HSP90AA1 (0.43) | KDM4EMAPTLMNAHSP90AA1L3MBTL1 | |
| SCHEMBL2892496 | 0.76 | KDM4E (0.43) | KDM4EMAPTLMNAHSP90AA1L3MBTL1 | |
| SCHEMBL2892994 | 0.76 | PSMD14 (0.43) | KDM4EMAPTLMNAHSP90AA1L3MBTL1 | |
| SCHEMBL15663106 | 0.76 | KDM4E (0.33) | KDM4EMAPTLMNAHSP90AA1L3MBTL1 | |
| SCHEMBL27623899 | 0.74 | PSMD14 (0.42) | KDM4EMAPTLMNAHSP90AA1L3MBTL1 | |
| SCHEMBL1716241 | 0.72 | NPC1 (0.34) | KDM4EMAPTLMNAHSP90AA1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341778-B | Synthetic method of phenanthridinone compound | 上海交通大学 | 2021-07-09 | — | — | CN | claimed |
| EP-3071205-B1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS INC (US) | 2020-02-05 | — | — | EP | claimed |
| US-10377769-B2 | Benzopiperazine compositions as BET bromodomain inhibitors | FORMA THERAPEUTICS, INC. (US) | 2019-08-13 | — | — | US | claimed |
| US-20180312524-A1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS, INC. | 2018-11-01 | — | — | US | claimed |
| US-20180140694-A1 | DOSAGE REGIMEN FOR HIV VACCINE | BIONOR IMMUNO AS (NO) | 2018-05-24 | — | — | US | claimed |
| US-9714560-B2 | Protected scale inhibitors and methods relating thereto | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-07-25 | — | — | US | claimed |
| WO-2016177833-A1 | DOSAGE REGIMEN FOR HIV VACCINE | BIONOR IMMUNO AS (NO) | 2016-11-10 | — | — | WO | claimed |
| EP-3071205-A1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | Forma Therapeutics, Inc. (US) | 2016-09-28 | — | — | EP | claimed |
| US-20160257699-A1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS, INC. | 2016-09-08 | — | — | US | claimed |
| US-9422281-B2 | Benzopiperazine compositions as BET bromodomain inhibitors | FORMA THERAPEUTICS, INC. (US) | 2016-08-23 | — | — | US | claimed |
| CN-102227162-A | Herbicide-safener combination | BAYER CROPSCIENCE AG | 2011-10-26 | — | — | CN | claimed |
| US-20100286165-A1 | SUBSTITUTED OXINDOLE COMPOUNDS | ABBOTT GMBH & CO. KG (DE) | 2010-11-11 | — | — | US | claimed |
| WO-2008107399-A1 | SUBSTITUTED OXINDOLE COMPOUNDS | ABBOTT GMBH & CO. KG (DE) | 2008-09-12 | — | — | WO | claimed |
| CN-1198507-C | Selective herbicides based on substituted phenylsulfonylaminocarbonyltriazolinones and safeners | BAYER AG (DE) | 2005-04-27 | — | — | CN | claimed |
| CN-1379622-A | Selective herbicides based on substituted phenylsulfonylaminocarbonyltriazolinones and safeners | BAYER AG (DE) | 2002-11-13 | — | — | CN | claimed |
| US-5739079-A | CEREAL, RICE, CORN CROP SAFENER MIXED WITH WEED HERBICIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | claimed |
| EP-0305201-B1 | Protected biotin derivatives | ZENECA LTD (GB) | 1996-12-04 | — | — | EP | claimed |
| EP-0305201-A2 | Protected biotin derivatives | ZENECA LIMITED (GB) | 1989-03-01 | — | — | EP | claimed |
| EP-0064796-B1 | PHOSPHORYLATING AGENT AND PROCESS FOR THE PHOSPHORYLATION OF ORGANIC HYDROXYL COMPOUNDS | UNILEVER N.V. (NL) | 1985-05-15 | — | — | EP | claimed |
| EP-0064796-A2 | Phosphorylating agent and process for the phosphorylation of organic hydroxyl compounds | UNILEVER N.V. (NL) | 1982-11-17 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312524-A1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | BRD4, BRPF3, BRD7 | KDM4E 199/4885MAPT 3623/4885LMNA 3164/4885 |
| US-10377769-B2 | Benzopiperazine compositions as BET bromodomain inhibitors | BRD4, BRPF3, BRD7 | KDM4E 199/4885MAPT 3623/4885LMNA 3164/4885 |
| US-20160257699-A1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | BRD4, BRPF3, BRD7 | KDM4E 199/4885MAPT 3623/4885LMNA 3164/4885 |
| US-20100286165-A1 | SUBSTITUTED OXINDOLE COMPOUNDS | OXTR, AVPR2, AVPR1A | KDM4E 4463/4885MAPT 4388/4885LMNA 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.