Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KLK3 | P07288 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745945 | 0.78 | ATM (0.48) | ATMALPLLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL8745939 | 0.75 | SMN1; SMN2 (0.35) | LMNAKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29662465 | 0.62 | ADRA2A (0.38) | KDM4ESMN1; SMN2KMT2AMEN1HSD17B10 | |
| SCHEMBL16293581 | 0.62 | PTGS1 (0.60) | LMNAKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16293537 | 0.62 | PTGS1 (0.60) | LMNAKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16293535 | 0.62 | PTGS1 (0.60) | LMNAKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL18560451 | 0.61 | ALDH1A1 (0.48) | LMNAKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL20855709 | 0.61 | ADRA2A (0.40) | LMNAKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL20855710 | 0.61 | ADRA2A (0.40) | LMNAKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7426724 | 0.61 | ADRA2A (0.45) | LMNAKDM4EKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |