Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KAT7 | O95251 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332802 | 0.79 | PRKDC (0.36) | ATMKDM4ELMNAMEN1KMT2A | |
| SCHEMBL8745937 | 0.78 | ATM (0.41) | ATMALPLKDM4ELMNASMN1; SMN2 | |
| SCHEMBL5752891 | 0.73 | HPGD (0.43) | KDM4ELMNAKMT2AGAAMGAM | |
| SCHEMBL4527520 | 0.73 | MALT1 (0.39) | LMNAMEN1KMT2APOLBMAPT | |
| SCHEMBL3253017 | 0.72 | ALDH1A1 (0.39) | KDM4ELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7426724 | 0.71 | ADRA2A (0.45) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL3988110 | 0.71 | ADRA2A (0.45) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL2228565 | 0.70 | GAA (0.43) | KAT7KAT6ALMNASMN1; SMN2KMT2A | |
| SCHEMBL3257150 | 0.70 | ACHE (0.38) | LMNAMEN1KMT2AHSD17B10ACHE | |
| SCHEMBL8745916 | 0.69 | GAA (0.59) | KDM4ESMN1; SMN2KMT2AHSD17B10ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672567-A | PRE- AND POST-EMERGENCE | ZENECA LIMITED (GB) | 1997-09-30 | — | — | US | disclosed |
| US-5670453-A | PYRAZINEARYL COMPOUND | ZENECA LIMITED (GB) | 1997-09-23 | — | — | US | disclosed |
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995029898-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |