Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745959 | 0.84 | HPGD (0.41) | HPGDRAB9AGAAALDH1A1CYP1A2 | |
| SCHEMBL8745966 | 0.81 | HPGD (0.37) | HPGDRAB9AALDH1A1CYP1A2LMNA | |
| SCHEMBL8745943 | 0.76 | NOTUM (0.37) | HPGDRAB9AGAAALDH1A1KDM4E | |
| SCHEMBL8745932 | 0.75 | NOTUM (0.36) | HPGDGAAALDH1A1KDM4EKMT2A | |
| SCHEMBL8745919 | 0.72 | HPGD (0.41) | HPGDRAB9ACYP1A2KDM4EPOLB | |
| SCHEMBL8745958 | 0.70 | GAA (0.42) | HPGDRAB9AGAAALDH1A1KDM4E | |
| SCHEMBL9028966 | 0.69 | HPGD (0.36) | HPGDRAB9AGAAALDH1A1CYP1A2 | |
| SCHEMBL8745948 | 0.64 | POLB (0.39) | HPGDRAB9AGAAALDH1A1CYP1A2 | |
| SCHEMBL8745912 | 0.64 | NOTUM (0.40) | RAB9AGAALMNAKDM4EPOLB | |
| SCHEMBL8745957 | 0.63 | SMN1; SMN2 (0.36) | HPGDRAB9AGAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |