Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745943 | 0.87 | NOTUM (0.37) | HPGDALDH1A1KDM4ECTSAGAA | |
| SCHEMBL8745919 | 0.86 | HPGD (0.41) | HPGDCYP1A2HSD17B10CYP3A4CYP2C19 | |
| SCHEMBL8745932 | 0.85 | NOTUM (0.36) | HPGDALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL8745952 | 0.84 | HPGD (0.42) | HPGDCYP1A2LMNAALDH1A1CYP3A4 | |
| SCHEMBL8745966 | 0.82 | HPGD (0.37) | HPGDCYP1A2LMNAALDH1A1CYP3A4 | |
| SCHEMBL9028966 | 0.76 | HPGD (0.36) | HPGDCYP1A2LMNAALDH1A1ITGB1 | |
| SCHEMBL8745917 | 0.75 | HPGD (0.41) | HPGDCYP1A2HSD17B10CYP3A4CYP2C19 | |
| SCHEMBL8745912 | 0.73 | NOTUM (0.40) | LMNAKDM4EKCNK3GAASMN1; SMN2 | |
| SCHEMBL8745948 | 0.73 | POLB (0.39) | HPGDCYP1A2LMNAALDH1A1CYP3A4 | |
| SCHEMBL8745957 | 0.73 | SMN1; SMN2 (0.36) | HPGDLMNAALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |