Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745959 | 0.82 | HPGD (0.41) | HPGDPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8745952 | 0.81 | HPGD (0.42) | HPGDPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8745943 | 0.78 | NOTUM (0.37) | HPGDPOLBALDH1A1KDM4ENPC1 | |
| SCHEMBL8745932 | 0.78 | NOTUM (0.36) | HPGDALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL8745919 | 0.68 | HPGD (0.41) | HPGDPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9028966 | 0.67 | HPGD (0.36) | HPGDCYP1A2LMNAALDH1A1RAB9A | |
| SCHEMBL8745912 | 0.65 | NOTUM (0.40) | POLBLMNATHRBKDM4ENPC1 | |
| SCHEMBL8745948 | 0.65 | POLB (0.39) | HPGDPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8745913 | 0.65 | NOTUM (0.36) | HPGDPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8745936 | 0.65 | KCNA5 (0.35) | POLBCYP1A2CYP3A4CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |