Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745946 | 0.87 | KDM4E (0.39) | NOTUMKDM4EKMT2ACNR2SGMS2 | |
| SCHEMBL8745913 | 0.85 | NOTUM (0.36) | NOTUMKDM4ECYP24A1KMT2ACNR2 | |
| SCHEMBL8745959 | 0.85 | HPGD (0.41) | KDM4EGAASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL8745943 | 0.85 | NOTUM (0.37) | NOTUMKDM4EKMT2AGAASMN1; SMN2 | |
| SCHEMBL9028966 | 0.83 | HPGD (0.36) | NOTUMCYP24A1GAACNR2SMN1; SMN2 | |
| SCHEMBL8745975 | 0.81 | GAA (0.36) | NOTUMKDM4EKMT2AGAACNR2 | |
| SCHEMBL8745966 | 0.78 | HPGD (0.37) | KDM4EKMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL8745952 | 0.75 | HPGD (0.42) | KDM4EKMT2AGAASGMS2SMN1; SMN2 | |
| SCHEMBL9270522 | 0.74 | MGLL (0.39) | KMT2AMEN1 | |
| SCHEMBL8745948 | 0.71 | POLB (0.39) | KDM4EKMT2AGAASGMS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |